Barrier is a summoner spell that is a self-targeted spell that shields your champion from damage for 2 seconds.
Barrier is great for absorbing the burst of enemy champions. As much as a squishy mid-lanner as much a tanky top-lanner, Barrier, if used at the right moment, will save from tough situations.
Barrier can be used despite any Crowd Control with the exception of suppression.
Many consider Barrier to be vastly inferior to Heal, namely because you can waste/mistime Barrier at any time while alive, it only affects one person, offers no speed boost, and only has around 100 extra effective health at max level. However, Barrier is not affected by Healing reduction.