If the spider does not hit an enemy before reaching the target location, it re-targets and chases down a nearby enemy, prioritizing champions. The spider's movement speed increases as it gets closer to its target.
If Elise transforms back into Human Form after having summoned the Spiderlings, any Spiderlings that were alive will be retained as Spiderling charges and will be re-summoned at Elise's next transformation with the same life they retracted with plus any that was gained from natural health regeneration. Human form spellcasts when there is a full complement of spiderlings will refresh health of damaged ones.
Spiderlings last until killed.
Spiderlings cannot be controlled, though they will prioritize Elise's target when attacking. If Elise has no current target, Spiderlings will automatically attack nearby enemies. However, they will not attack neutral monsters on their own.
Enemy turrets will prioritize Spiderlings directly above the chain of melee minions.
Turrets kill Spiderlings with one hit regardless of the Spiderlings armor and HP.