As with other aura items such as Abyssal Scepter, Frozen Heart's debuff can give away potential ganks.
Frozen Heart is an item best suited for tank champions because of the high amount of armor and cooldown reduction but can also be useful for tanky support champions.
Ryze is an excellent candidate for use with the Frozen Heart, since the damage of his abilities is increased with his maximum mana. The added mana and cooldown reduction also gives him extra sustainability in lane and the armor reduces physical damage taken.
For its combine cost of 550 gold, Frozen Heart gives 100 mana, 10% cooldown reduction, and an attack speed reducing aura.
The icon used for Frozen Heart is the same icon from the popular online MMO game, World of Warcraft, used to represent a 'Citrine' gem. In this game, the gem appears orange.
The item's description "Warning: Do not thaw!" is a reference to the item Eye of Skadi from the mod DotA: Allstars, whose description contains the exact same line.
The Frozen Brain was a seasonal item for the 2010 Harrowing celebration. It has the same stats as the Frozen Heart, just a different name and picture.