- Kha'Zix's production name was 'Teek'.
- Ryan 'Morello' Scott stated Kha'Zix is completely unrelated to canceled champion .
- Kha'Zix was the last champion to feature an 'Art Spotlight'.
- When concealing himself (going in brush or using ) Kha'Zix will run in a different manner than usual.
- When acquiring and [ | ] do the same) [ | ] Kha'Zix will fly for a few seconds while moving (
- The Hunt is On! between Kha'Zix and references .
- references (Kha'Zix's main inspiration)
- Being an arthropodic invader from another world with scythes as his primary weapon, he also bears a striking resemblance to the real-life Metroid's Space Pirates, though he also possesses beetles' hardened outer wings. &
- projectiles might be referencing a from .
- Kha'Zix can spend evolution points on abilities he has not learned yet (doing this only benefits
for the bonus range on basic attacks)
- Kha'Zix must spend evolution points before ranking up any ability if he has any unspent points after ranking up .
- Kha'Zix is the only Voidborn champion without true damage on any ability (unlike , , , , and )
- "Change... is good" references .
- "To truly know someone, eat them and walk a mile in their feet" might be referencing by .
- Kha'Zix and "Limb from limb". share the quote
- [ | ]
- He has acquired , , and is to .
- His / pose might be referencing from .
- [ | ]
- He was the first release skin priced at 1350 (was bundled at 975 rather than the usual 50% discount)
- He has a single dedicated joke as well as animations when being stunned or knocked airborne.
- He is the second non-Legendary skin with special voice-over lines (the others being , [ | ], [ | ], and [ | ]) [ | ]
- becomes a flurry of rockets fired in a manner referencing from .
- He shares this theme with , [ | ], [ | ], and [ | ] [ | ]
- [ | ]
- His eyes are red but emerald-green in-game.
- He resembles a and/or .
- He might be referencing the from .
- He shares this theme with , [ | ], [ | ], and [ | ]. [ | ]
- [ | ]
- Helmet Bro can be seen in the foreground.
- He is based on the .
- He shares this theme with . [ | ]
- Kha'Zix, the Voidborn. , , , and each belong to different member species of the collective known as
- Kha'Zix seeks to consume in order to evolve into the ultimate predator.