Runes are enhancements that the Summoner provides to their champion. If the outlining color of the rune you've placed matches the color of the slot you put it in, it's a primary. If it doesn't match then it's a secondary and you get a significantly lower bonus, except in the case of some quintessences which give as good or better bonuses than the primary runes, listed below. This table is also available in spreadsheet format displayed by name or by primary.

Primary runesEdit

• Primary Marks:
  • Armor Penetration
  • Attack Damage
  • Attack Speed
  • Critical Chance
  • Critical Damage
  • Hybrid Penetration (Armor Penetration / Magic Penetration)
  • Magic Penetration
  • Scaling Attack Damage (Attack Damage per level)

• Primary Seals:
  • Armor
  • Energy Regeneration
  • Gold (Gold / 10 sec)
  • Health
  • Health Regeneration
  • Mana Regeneration
  • Percent Health
  • Scaling Armor (Armor per level)
  • Scaling Energy Regeneration (Energy Regen / 5 sec per level)
  • Scaling Health (Health per level)
  • Scaling Health Regeneration (Health Regen / 5 sec per level)
  • Scaling Mana Regeneration (Mana Regen / 5 sec per level)

• Primary Glyphs:
  • Ability Power
  • Cooldown Reduction
  • Energy
  • Magic Resist
  • Mana
  • Scaling Ability Power (Ability Power per level)
  • Scaling Cooldown Reduction (Cooldown Reduction per level)
  • Scaling Energy (Energy per level)
  • Scaling Magic Resist (Magic Resist per level)
  • Scaling Mana (Mana per level)

• Primary Quintessences are utility runes, many of which may only be found as quintessences. A purple outline around the placed rune indicates that it's a primary. The quintessences below are either primary or surpass 3 primary runes of their color.
  • Ability Power
  • Armor
  • Gold (Gold / 10 sec)
  • Health
  • Health Regeneration
  • Mana
  • Mana Regeneration
  • Percent Health
  • Scaling Mana Regeneration (Mana Regen / 5 sec per level)

• Unique Quintessences are utility runes that can only be found as a quintessence.
  • Experience
  • Life Steal
  • Movement Speed
  • Revival (Reduction of Time Dead)
  • Spell Vamp

Seasonal Event Runes Edit

Additionally, unique runes were sold during the 2009 Snowdown Showdown, 2010 Winter Games Celebration, 2010 Harrowing, and the 2010 Snowdown Showdown. The ones sold during the 2009 Snowdown Showdown, 2010 Winter Games Celebration, and 2010 Harrowing are not equivalent to Lesser, Normal, or Greater Tier runes, but instead occupy Tiers 1.5 and 2.5, between Lesser/Normal and Normal/Greater, respectively. Those sold during the 2010 Snowdown Showdown are Tier 3 (Greater) runes, at a 25% reduced price of their counterparts.

2009 Snowdown Showdown Edit

• Mark of the Crippling Candy Cane (Tier 2.5, critical damage)
• Glyph of the Special Stocking (Tier 2.5, cooldown reduction)
• Seal of the Elusive Snowflake (Tier 2.5, dodge chance)
• Mark of the Yuletide Tannenbaum (Tier 1.5, critical chance)
• Glyph of the Gracious Gift (Tier 1.5, AP per level)
• Seal of the Stout Snowman (Tier 1.5, HP per level)

2010 Winter Games Celebration Edit

• Mark of the Combatant (Tier 2.5, critical damage)
• Lesser Mark of Alpine Alacrity (Tier 1.5, attack speed)
• Seal of the Extreme (Tier 2.5, dodge)
• Lesser Seal of the Medalist (Tier 1.5, health)
• Glyph of the Soaring Slalom (Tier 2.5, cooldown reduction)
• Lesser Glyph of the Challenger (Tier 1.5, AP per level)

2010 Harrowing Edit

• Quintessence of the Piercing Screech (Tier 2.5, +1.75 Magic Penetration)
• Quintessence of Bountiful Treats (Tier 2.5, +24 Health)
• Quintessence of the Speedy Specter (Tier 2.5, +1.39% Movement Speed)
• Quintessence of the Elusive Werewolf (Tier 2.5, +1.39% Dodge)
• Quintessence of the Witches Brew (Tier 2.5, +4.56 Ability Power)
• Quintessence of the Headless Horseman (Tier 2.5, +3.62 3.08 Armor Penetration)

2010 and 2011 Snowdown Showdown Edit

• Greater Quintessence of Frosty Fortitude - Health
• Greater Quintessence of Sugar Rush - Movement Speed
• Greater Quintessence of the Piercing Present - Magic Penetration
• Greater Quintessence of the Deadly Wreath - Armor Penetration

2011 Razer Runes Promotion Edit

• Razer Quintessence of Speed - Movement Speed
• Razer Mark of Precision - Critical Damage

2011 Harrowing Edit

• Quintessence of the Piercing Screech (Tier 2.5, +1.75 Magic Penetration)
• Quintessence of Bountiful Treats (Tier 2.5, +24 Health)
• Quintessence of the Speedy Specter (Tier 2.5, +1.39% Movement Speed)
• Quintessence of the Elusive Werewolf (Tier 2.5, +1.39% Dodge)
• Quintessence of the Witches Brew (Tier 2.5, +4.56 Ability Power)
• Quintessence of the Headless Horseman (Tier 2.5, +3.08 Armor Penetration)

Other Edit

• Greater Quintessence of Studio Rumble (+1.5% Movement Speed), from exclusive Riot & Gaming Industry-only tournament on Dec 2011.

Full Runes List Edit

Name	Type	Tier 1 (Lesser)	Tier 2 (Normal)	Tier 3 (Greater)
Ability Power	Mark	0.33 30	0.46 165	0.59 410
	Seal	0.33 30	0.46 165	0.59 410
	Glyph	0.66 30	0.92 165	1.19 410
	Quintessence	2.75 80	3.85 410	4.95 1025
Armor	Mark	0.51 15	0.71 80	0.91 205
	Seal	0.78 15	1.09 80	1.41 205
	Glyph	0.39 15	0.55 80	0.7 205
	Quintessence	2.37 80	3.32 410	4.26 1025
Armor Penetration	Mark	0.72 30	1 165	1.28 410
	Seal
	Glyph
	Quintessence	1.42 80	1.99 410	2.56 1025
Attack Damage	Mark	0.53 15	0.74 80	0.95 205
	Seal	0.24 15	0.33 80	0.43 205
	Glyph	0.16 15	0.22 80	0.28 205
	Quintessence	1.25 80	1.75 410	2.25 1025
Attack Speed	Mark	0.94% 30	1.32% 165	1.7% 410
	Seal	0.42% 30	0.59% 165	0.76% 410
	Glyph	0.35% 30	0.5% 165	0.64% 410
	Quintessence	1.89% 80	2.64% 410	3.4% 1025
Cooldown Reduction	Mark	0.11% 30	0.16% 165	0.2% 410
	Seal	0.2% 30	0.29% 165	0.36% 410
	Glyph	0.47% 65	0.67% 330	0.83% 820
	Quintessence	0.93% 165	1.33% 820	1.67% 2050
Critical Chance	Mark	0.52% 30	0.72% 165	0.93% 410
	Seal	0.23% 30	0.32% 165	0.42% 410
	Glyph	0.15% 30	0.22% 165	0.28% 410
	Quintessence	1.03% 80	1.44% 410	1.86% 1025
Critical Damage	Mark	1.24% 65	1.74% 330	2.23% 820
	Seal	0.43% 65	0.61% 330	0.78% 820
	Glyph	0.31% 65	0.43% 330	0.56% 820
	Quintessence	2.48% 80	3.47% 410	4.46% 1025
Energy	Mark
	Seal
	Glyph			2.2 820
	Quintessence			5.4 1025
Energy Regeneration (Energy Regen / 5 sec)	Mark
	Seal			0.63 820
	Glyph
	Quintessence			1.575 2050
Experience	Mark
	Seal
	Glyph
	Quintessence			2% 2050
Gold (Gold / 10 sec)	Mark
	Seal			0.25g 410
	Glyph
	Quintessence			1g 515
Health	Mark	1.93 30	2.7 165	3.47 410
	Seal	2.97 65	4.16 330	5.35 820
	Glyph	1.49 30	2.08 165	2.67 410
	Quintessence	14.5 165	20 820	26 2050
Health Regeneration (Health Regen / 5 sec)	Mark
	Seal	0.24 65	0.34 330	0.43 820
	Glyph	0.15 65	0.21 330	0.27 820
	Quintessence	1.5 165	2.1 820	2.7 2050
Hybrid Penetration (Armor Penetration / Magic Penetration)	Mark	0.5 / 0.34 65	0.7 / 0.48 330	0.9 / 0.62 820
	Seal
	Glyph
	Quintessence	0.99 / 0.78 165	1.39 / 1.09 820	1.79 / 1.4 2050
Life Steal	Mark
	Seal
	Glyph
	Quintessence	1.12% 165	1.56% 820	2% 2050
Magic Penetration	Mark	0.49 30	0.68 165	0.87 410
	Seal
	Glyph	0.35 30	0.49 165	0.63 410
	Quintessence	1.11 80	1.56 410	2.01 1025
Magic Resist	Mark	0.43 15	0.6 80	0.77 205
	Seal	0.41 15	0.58 80	0.74 205
	Glyph	0.74 15	1.04 80	1.34 205
	Quintessence	2.22 80	3.11 410	4 1025
Mana	Mark	3.28 30	4.59 165	5.91 410
	Seal	3.83 30	5.36 165	6.89 410
	Glyph	6.25 30	8.75 165	11.25 410
	Quintessence	20.83 80	29.17 410	37.5 1025
Mana Regeneration (Mana regen / 5 sec)	Mark	0.15 15	0.2 80	0.26 205
	Seal	0.23 15	0.32 80	0.41 205
	Glyph	0.17 30	0.24 165	0.31 410
	Quintessence	0.69 80	0.97 410	1.25 1025
Movement Speed	Mark
	Seal
	Glyph
	Quintessence	0.83% 165	1.17% 820	1.5% 2050
Percent Health	Mark
	Seal	0.28% 65	0.39% 330	0.5% 820
	Glyph
	Quintessence	0.84% 165	1.17% 820	1.5% 2050
Revival (Reduction of time dead)	Mark
	Seal
	Glyph
	Quintessence			5% 1025
Scaling Ability Power (Ability Power per level)	Mark	0.06 per level (1.08) 30	0.08 per level (1.44) 165	0.1 per level (1.8) 410
	Seal	0.06 per level (1.08) 30	0.08 per level (1.44) 165	0.1 per level (1.8) 410
	Glyph	0.1 per level (1.8) 30	0.13 per level (2.34) 165	0.17 per level (3.06) 410
	Quintessence	0.24 per level (4.32) 80	0.34 per level (6.12) 410	0.43 per level (7.74) 1025
Scaling Armor (Armor per level)	Mark
	Seal	0.08 per level (1.44) 30	0.12 per level (2.16) 165	0.15 per level (2.7) 410
	Glyph
	Quintessence	0.21 per level (3.78) 80	0.29 per level (5.22) 410	0.38 per level (6.84) 1025
Scaling Attack Damage (Attack Damage per level)	Mark	0.08 per level (1.35) 30	0.1 per level (1.89) 165	0.13 per level (2.43) 410
	Seal	0.03 per level (0.61) 15	0.05 per level (0.85) 80	0.06 per level (1.09) 205
	Glyph	0.02 per level (0.36) 15	0.03 per level (0.57) 80	0.04 per level (0.73) 205
	Quintessence	0.14 per level (2.52) 40	0.19 per level (3.42) 205	0.25 per level (4.5) 515
Scaling Cooldown Reduction (Cooldown Reduction per level)	Mark
	Seal
	Glyph	0.04% per level (0.72%) 30	0.05% per level (0.9%) 165	0.06% per level (1.11%) 410
	Quintessence	0.08% per level (1.44%) 80	0.11% per level (2%) 410	0.14% per level (2.5%) 1025
Scaling Energy (Energy per level)	Mark
	Seal
	Glyph			0.161 per level (2.89) 820
	Quintessence
Scaling Energy Regeneration (Energy Regen / 5 sec per level)	Mark
	Seal			0.064 per level (1.15) 820
	Glyph
	Quintessence
Scaling Health (Health per level)	Mark	0.3 per level (5.4) 65	0.42 per level (7.56) 330	0.54 per level (9.72) 820
	Seal	0.6 per level (10.8) 30	0.84 per level (15.12) 165	1.08 per level (19.44) 410
	Glyph	0.3 per level (5.4) 65	0.42 per level (7.56) 330	0.54 per level (9.72) 820
	Quintessence	1.5 per level (27) 165	2.1 per level (37.8) 820	2.7 per level (48.6) 2050
Scaling Health Regeneration (Health Regen / 5 sec per level)	Mark
	Seal	0.06 per level (1.08) 30	0.09 per level (1.62) 165	0.11 per level (1.98) 410
	Glyph
	Quintessence	0.16 per level (2.88) 165	0.22 per level (3.96) 820	0.28 per level (5.04)
Scaling Magic Resist (Magic Resist per level)	Mark	0.04 per level (0.72) 15	0.06 per level (1.08) 80	0.07 per level (1.26) 205
	Seal	0.05 per level (0.9) 30	0.08 per level (1.44) 165	0.1 per level (1.8) 410
	Glyph	0.08 per level (1.44) 15	0.12 per level (2.16) 80	0.15 per level (2.7) 205
	Quintessence	0.21 per level (3.78) 80	0.29 per level (5.22) 410	0.37 per level (6.66) 1025
Scaling Mana (Mana per level)	Mark	0.65 per level (11.7) 30	0.91 per level (16.38) 165	1.17 per level (21.06) 410
	Seal	0.65 per level (11.7) 30	0.91 per level (16.38) 165	1.17 per level (21.06) 410
	Glyph	0.79 per level (14.22) 30	1.1 per level (19.8) 165	1.42 per level (25.56) 410
	Quintessence	2.31 per level (41.58) 40	3.24 per level (58.32) 205	4.17 per level (75.06) 515
Scaling Mana Regeneration (Mana regen / 5 sec per level)	Mark
	Seal	0.036 per level (0.65) 15	0.05 per level (0.9) 80	0.065 per level (1.17) 205
	Glyph	0.03 per level (0.54) 15	0.04 per level (0.72) 80	0.055 per level (0.99) 205
	Quintessence	0.14 per level (2.52) 80	0.19 per level (3.42) 410	0.24 per level (4.32) 1025
Spell Vamp	Mark
	Seal
	Glyph
	Quintessence	1.12% 165	1.56% 820	2% 2050

Runes
Glyphs Marks Seals Quintessences Runebook List of runes